WebThe biosynthesis of both phytotoxins is predicted to occur on multifunctional enzyme complexes by the thiotemplate mechanism. The syringomycin (syr) gene cluster lies … Webthio-template mechanism to synthesize secondary metabolites. Compared to other template mechanisms, including those in polynucleotide and polypeptide synthesis, the thiotemplate mechanism features intensive modifications in the linear exten-sion stage, leading to more diversified structures in the product
Occurrence and Biosynthetic Mechanism of Poly-Gamma …
WebJan 15, 2002 · Biosynthesis of Peptide Antibiotics. K. Kurahashi. Biology, Chemistry. 1981. TLDR. The author considers that it describes best the novel type of peptide biosynthesis and proposes to term it the ‘multienzyme thiotemplate mechanism’. 11. WebPseudomonas syringae pv.syringae strain B301D produces the lipodepsipeptide Phytotoxins, syringomycin and syringopeptin. Analysis of the syringomycin (syr) gene cluster of strain B301D indicated that the toxin is synthesized on multienzymes by a thiotemplate mechanism of peptide synthesis.The syr genes encoding syringomycin synthetases were … cvp atomos
Effect of media and fermentation conditions on surfactin and …
WebThe thiotemplate mechanism of peptide synthesis utilizes multifunctional enzymes, called peptide synthetases, that catalyze the activation and addition of amino acids to the growing peptide chain ... WebAlthough the precise function of the gene products needs further clarification, a biosynthetic pathway based on a multienzyme thiotemplate mechanism allowing a step-by-step synthesis of the whole chromopeptide molecule can be postulated. WebJan 1, 2010 · The thiotemplate mechanism is catalyzed by nonribosomal peptide synthetases (NRPSs). NRPSs are often called multienzyme systems because of the … raija uosikkinen arabia